Head of Oligonucleotides Platform2025 July 30th, Closing Date :30 Sep 2025 Organization: Platform Technology Location: Singapore Job Type: Senior Leadership | Full Time
About NATi The Nucleic Acid Therapeutics Initiative (NATi), hosted by A*STAR, is Singapore's national platform dedicated to advancing RNA-based medicines and revolutionizing drug and vaccine development. NATi's mission is to establish Singapore as a globally recognized hub of excellence in nucleic acid therapeutics research, clinical translation, and commercialization. NATi focuses on key RNA modalities such as antisense oligonucleotides (ASOs), small interfering RNA (siRNA), and messenger RNA (mRNA). To drive this vision, NATi is building a biotech-like translational engine focused on asset and technology development spanning discovery to clinical development. We are actively seeking passionate and committed RNA scientists with deep translational expertise to join us in advancing the next generation of RNA-based therapeutics.
Position Overview The Head of Oligonucleotides Platform will build and lead a robust and fully integrated oligonucleotides (e.g., ASO, siRNA) research organization to support the discovery, production, preclinical development, and translation of oligonucleotides Drug Candidates. This role demands deep expertise across the different elements of the synthetic oligonucleotides technology to ensure readiness and to position the platform to operate as a robust engine for development of gene silencing medicines. This leader will work closely with the NATi Managing Director to develop and execute the strategy for the Oligonucleotides Platform. They will establish productive partnerships with the heads of therapeutic areas to collaboratively develop the next wave of RNA medicines. Additionally, this leader will play a critical role in defining the innovation agenda for the oligonucleotides platform and oversee strategic partnerships with global collaborators focused on unlocking the full potential of ASO/siRNA modality.
Key Responsibilities
Qualifications & Experience
Global Recruitment & Competitive Compensation NATi is conducting a global search for top-tier talent in mRNA therapeutics. We welcome applications from leading scientists and biotech innovators worldwide. This role provides a highly competitive compensation package aligned with global industry standards, including attractive benefits and long-term career growth opportunities within Singapore's thriving ecosystem. Join us in shaping the future of RNA-based medicines and establishing Singapore as a world-class hub for nucleic acid therapeutics.
The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.
Type of Employment: Full-Time Minimum Experience: 12 Years Work Location: Biopolis
Link to The Career Website: Career - Agency for Science, Technology and Research |