Postdoctoral Position in the laboratory of RNA Biology and Therapeutics, University of Kansas Medical Center

Posted on August 19th, 2025

A postdoctoral position is available in the laboratory of RNA Biology and Therapeutics (https://kumc-staging.ingeniuxondemand.com/school-of-medicine/academics/departments/biochemistry-and-molecular-biology/research/kharel-lab) in the Department of Biochemistry and Molecular Biology (BMB), University of Kansas Medical Center (KUMC). The Kharel Lab is looking for the applicants with interests in studying RNA biology in human neurological disorders. Particularly, an interest in studying G-quadruplex biology from both biological and therapeutic aspects is desired. Applied methods range from the use of biochemical, biophysical, molecular, cellular, and bioinformatics approaches. Collaboration with structural biologists is possible.

Applicants should hold a PhD or equivalent degree in Biochemistry, Molcular Biology, Cell Biology, or related fields. Applicants should be self-driven, highly motivated and capable of planning and conducting independent research under the PI’s supervision while being willing to collaborate. Practical experience in RNA and/or protein biochemistry, including the expression and purification of recombinant proteins and the functional analysis of proteins and RNA-protein complexes is desired. Experience in investigating aspects of eukaryotic translation and associated quality control processes will be highly appreciated. Candidates should be able to work independently and show excellent critical thinking, scholarly ability and communication skills.

Job Description

Key Roles and Responsibilities:

  • Conduct research, record data, analyze data, and interpret experimental results.
  • Read literature articles, develop new ideas, and assimilate the information into his/her project design/interpretation.
  • Prepare manuscripts for publishing in peer-reviewed scientific journals.
  • Present research findings at conferences and scientific meetings.
  • Collaborate with fellow lab members, including graduate students and technicians, to achieve research objectives. Share expertise and contribute to a collaborative and dynamic research environment.
  • Submit fellowship applications, as eligible, to bolster research funding and CV building for projects.

    Required Qualifications
  • PhD or equivalent terminal degree in Biochemistry, Chemical Biology, Molecular Biology,Cell Biology, or a related field.
  • Demonstrated experience in cutting edge techniques in RNA Biology, protein biochemistry, neuromuscular biology, and cell biology.

Preferred Qualifications

  • Proficiency in using biophysical tools, such as circular dichroism, microscale thermophoresis, etc.
  • Highthroughput data analysis (RNA-seq/ Proteome).
  • Experience working with mouse model of neuro/muscular disorders.